“Let us, then, form the provisional theory that every nine days the professor takes some strong drug which has a passing but highly poisonous effect. His naturally violent nature is intensified by it. He learned to take this drug while he was in Prague, and is now supplied with it by a Bohemian intermediary in London."

“If the cycle of nine days holds good then we shall have the professor at his worst to-night,” said Holmes. “The fact that these strange symptoms began after his visit to Prague, that he is in secret correspondence with a Bohemian dealer in London, who presumably represents someone in Prague, and that he received a packet from him this very day, all point in one direction."

"He takes it under definite directions which regulate this ninth-day system, which was the first point which attracted my attention. But his symptoms are most remarkable. Did you observe his knuckles?”

“Thick and horny in a way which is quite new in my experience. Always look at the hands first, Watson. Then cuffs, trouser-knees, and boots. Very curious knuckles which can only be explained by the mode of progression observed by —” Holmes paused and suddenly clapped his hand to his forehead. “Oh, Watson, Watson, what a fool I have been! It seems incredible, and yet it must be true. All points in one direction. How could I miss seeing the connection of ideas? Those knuckles how could I have passed those knuckles? And the dog! And the ivy!"

“The real source,” said Holmes, “lies, of course, in that untimely love affair which gave our impetuous professor the idea that he could only gain his wish by turning himself into a younger man."

"The dog, of course, was aware of the change far more quickly than you. His smell would insure that. It was the monkey, not the professor, whom Roy attacked, just as it was the monkey who teased Roy. Climbing was a joy to the creature, and it was a mere chance, I take it, that the pastime brought him to the young lady’s window."

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